I recently created a rule that sends email to the Clutter folder if it has the text "unsubscribe" in the email body. It is literally the best. I look once a week to make sure there's nothing I actually want to deal with, otherwise trash it all. – Is It Over Yet?
Currently popular on Mefi: Best Practices for Outlook, time management tips for "the behemoth of O365." A guide from the product team that created Microsoft Outlook, plus Mefites share their own hacks.